Formatted Title
Benefits of Co-Solvation Methods for Non-Target PFAS Analytes
Background/Objectives
We’ve come a long way since the first available PFAS method. Technology, technique, and demand for testing has increased. PFAS testing is critical in the effort to identify, remediate, and eliminate source materials, which in turn helps our environment and protects human health. The more we learn about PFAS, the more we understand the serious impact it is having on our ecosystem. Instrument sensitivity and the understanding of how and where the contaminants are found in the laboratory has changed the landscape of testing.
Approach/Activities
Co-solvation (a direct inject method) is ideal for testing analytes as they transition from non-target to target PFAS compounds. Combustion methods are good for total analyses, but they do not have the ability to speciate. Accurate mass instrumentation (e.g., QTOF) is great for compound identification, but it is not ideal for quantitation. A direct inject method eliminates the need for choosing an SPE (solid phase extraction) cartridge, which is beneficial since SPE is a layer of selectivity that presents an additional hurdle for new analytes. Direct injection bypasses SPE obstacles, which streamlines and optimizes method development, allowing a quicker and more dependable response to rapidly evolving PFAS testing needs.
Results/Lessons Learned
This presentation explores the unique advantages of direct inject methods and helps transition from non-target compounds to quantitative actionable results.